How fast does sildenafil work?

Gepubliceerd op
22/1/25
Laatste update
25/1/2026
De samenvatting

Sildenafil, the active substance in Viagra, treats erection problems by increasing blood flow to the penis by inhibiting the enzyme PDE5. It works within 30-60 minutes, depending on metabolism and food intake, and remains effective for around four hours. Side effects such as headache and flushing are mild and temporary. At Fellos, after an online consultation, you will discreetly receive a prescription with free home delivery.

What is sildenafil?

Sildenafil is the active substance in the well-known drug Viagra. Originally developed by Pfizer, Viagra was introduced in 1998 as a treatment for erectile dysfunction. The patent has now expired and sildenafil is being offered as a generic medicine. As a generic drug with the same effectiveness and safety, the price for sildenafil has fallen significantly compared to the branded product Viagra. Sildenafil and Viagra are available by prescription only. At Fellos, you can receive a doctor's prescription after a short online intake. This is how we guarantee professional and quality care without awkward conversations.

How long does it take for sildenafil to work?

After ingestion, it usually takes 30 to 60 minutes before sildenafil starts to work. The induction time may vary slightly depending on various factors. If you have a fast metabolism, your treatment may start to work faster. If you have a slow metabolism, it can actually take longer. What you have eaten can also affect the processing time; a heavy meal can make it take longer for your treatment to start working. We recommend not eating too heavy before taking sildenafil or Viagra. Finally, a higher dose can result in a faster absorption time. However, a higher dosage also increases the risk of side effects such as headache, flushing and muscle pain. We therefore recommend taking the lowest possible dose. If you want your treatment to take effect faster, it is better to eat a little lighter before ingestion.

It is important to note that sildenafil only works in combination with sexual stimulation. Without sexual stimulation, you will therefore not get an erection. The effect usually lasts around four hours.

What happens after taking sildenafil?

Sildenafil is a PDE5 inhibitor and works by inhibiting a specific enzyme: phosphodiesterase type 5 (PDE5). This enzyme plays a role in the breakdown of cGMP, a molecule that is essential for the relaxation of smooth muscles in the blood vessels. By inhibiting PDE5, sildenafil increases the levels of cGMP in the body. This leads to improved blood flow to the penis, which causes harder erections. And helps with both getting and maintaining an erection.

The effects of sildenafil are dependent on sexual stimulation; it does not work without any form of stimulation. As a result, the natural process is supported and sildenafil facilitates obtaining and maintaining an erection during sexual activity.

Sildenafil works by increasing blood flow to the penis, which helps to get and maintain an erection. It does this by inhibiting the action of an enzyme that constricts blood vessels. This process supports natural responses to sexual stimuli.

What are the side effects of sildenafil?

As with other medications, side effects may occur. Possible side effects include headache, flushing, upset stomach and nasal congestion. These symptoms are usually mild and disappear after the sildenafil starts to work out. Consult a doctor if you experience serious or long-term side effects. At Fellos, a thorough medical assessment is always carried out digitally based on the completed questionnaire by one of our doctors. In order to minimize any risks.
A comprehensive overview of all possible side effects can be found in the FAQ on the sildenafil medication page.

When can you use sildenafil?

Sildenafil is suitable for men who erection problems experienced and have been prescribed a prescription by a doctor. Do not use the medicine more than once a day and always follow your doctor's advice. At Fellos, you can easily get in touch with a experienced doctor via a (chat) consultation. The doctor will assess your situation and prescribe a prescription if possible.

What are the benefits of sildenafil?

Effectiveness: Sildenafil has been clinically proven effective for treating erectile dysfunction. Out research it appears that sildenafil is effective in 94% of users. Which indicate that their sexual performance has significantly improved.
Safety: Sildenafil is a safe treatment used by millions of men worldwide. Sildenafil has also been proven effective and has been approved by competent authorities such as the European EMA and Dutch MEB.
Availability: Since the patent on Viagra expired, affordability and availability have improved.
Discretion: At Fellos, your medication is delivered discreetly to your home, without awkward conversations in person with a doctor.

Bronnen

Fellos hanteert strikte redactionele richtlijnen voor bronnen om de nauwkeurigheid en actualiteit van onze inhoud te waarborgen. Onze inhoud is gebaseerd op wetenschappelijke publicaties, onderzoek van academische instellingen en gerenommeerde medische organisaties. Zie je een fout? Laat het ons weten via [email protected].

Dit artikel is uitsluitend bedoeld voor informatieve doeleinden en vormt geen medisch advies. De informatie hierin is geen vervanging voor professioneel medisch advies en mag hier nooit op worden vertrouwd. Bespreek de risico's en voordelen van elke behandeling altijd met je arts.

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25/1/2026

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